Enterprise MCP Guide For Healthcare Providers: Use Cases, Best Practices, and Trends

Enterprise MCP Guide For Healthcare Providers: Use Cases, Best Practices, and Trends

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Arcade.dev Team
NOVEMBER 17, 2025
16 MIN READ
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Healthcare leaders recognize automation's urgency: 92% cite automation as critical for addressing staff shortages. Yet only 30% of AI pilots reach production due to integration and multi-user authorization barriers. Model Context Protocol (MCP) solves the M×N integration problem blocking deployment at scale. Your Electronic Health Record has an API. Your data warehouse has an API. Your billing system has an API. But your AI agents can't securely act on behalf of multiple users across these systems—at least not without massive custom integration work. As an MCP-compatible runtime, Arcade enables healthcare providers to implement secure, multi-user authorization across clinical and operational systems—finally making AI agents production-ready in HIPAA-compliant environments.

Key Takeaways

  • Model Context Protocol (MCP) is the universal connector enabling AI agents to securely access healthcare data sources through standardized client-server architecture, eliminating the M×N custom integration problem
  • 92% of healthcare leaders say automation is critical for addressing staff shortages; data interoperability across fragmented systems remains a major barrier MCP addresses
  • Prior authorization automation delivers measurable ROI, with healthcare providers reporting significant reductions in processing time and denial rates through MCP-enabled workflows
  • Physicians spend 35% of their time on administrative tasks; MCP-powered patient communication and clinical documentation tools return hours to direct care
  • Healthcare-specific MCP implementations (HMCP) provide built-in HIPAA safeguards including patient identity segregation, audit trails for every AI action, and policy-based guardrails
  • Clinical decision support systems can reduce medication errors by approximately 30-50%; MCP provides the integration layer enabling such CDSS capabilities to access EHR and drug databases securely
  • Multi-user authorization—not just OAuth login—is the core challenge MCP addresses, enabling granular permissions and scopes for each agent action
  • Production-ready MCP deployments require comprehensive governance frameworks, human-in-the-loop approval for high-stakes actions, and continuous monitoring of AI accuracy metrics
  • The "prove-it era" of healthcare AI demands measurable outcomes; organizations must implement single use cases first to demonstrate ROI before scaling enterprise-wide

Enterprise MCP Use Cases for Healthcare Providers

Understanding MCP's Role in Healthcare AI Infrastructure

Model Context Protocol creates a standardized translation layer between AI models and healthcare systems. Instead of building separate custom APIs for each AI application to access each data source, MCP provides one universal protocol that any MCP-compatible AI can use to securely query any MCP-enabled system. This architectural shift transforms what was previously an M×N integration problem—requiring 15 separate connections for 3 AI tools across 5 data sources—into an M+N solution requiring just 8 standardized connections.

For healthcare executives, this means your AI agents can now access Electronic Health Records through FHIR APIs, query clinical data warehouses, verify insurance eligibility, and schedule appointments across different systems within unified workflows—all while maintaining complete audit trails and HIPAA compliance.

This is where platforms like Arcade as MCP runtime govern multi-user authorization across your tool catalog, managing token and secret lifecycles and enabling fine-grained, delegated user permissions that traditional point-to-point integration approaches can’t realistically replicate.

Prior Authorization Automation: Solving Revenue Cycle Bottlenecks

Healthcare providers spend substantial portions of their budgets on custom API integrations for revenue cycle operations. Prior authorization requests traditionally require manual chart review, documentation compilation, and payer portal navigation—causing treatment delays and administrative burden that impacts both patient care and organizational efficiency.

MCP-enabled AI agents access clinical documentation from EHR systems, retrieve diagnosis and procedure codes from billing platforms, and query payer policy databases through standardized connections. The AI compiles complete prior authorization packets with supporting clinical documentation automatically, then routes submissions through appropriate approval workflows.

Measurable outcomes from healthcare organizations implementing MCP for prior authorization include:

  • Significant reductions in processing time from days to hours
  • Decreased denial rates through more complete documentation
  • Faster treatment approvals improving patient satisfaction
  • Reduced administrative overhead freeing staff for complex cases

Implementation requires EHR FHIR API access, payer policy database integration (often through Elasticsearch MCP servers), and billing system connections. Organizations often begin seeing measurable improvements within a few months of deployment, depending on integration complexity and payer mix.

Patient Communication Automation at Scale

Physicians spend 35% of their time on administrative tasks rather than direct patient care. Patient inquiries regarding appointment requests, medication questions, and test result explanations create email backlogs and extended phone hold times that degrade patient experience while consuming valuable clinical resources.

MCP-enabled solutions like Arcade's Gmail integration connect AI assistants to patient email systems with HIPAA controls. The AI analyzes inquiry content and patient history through secure EHR access to generate contextually appropriate responses. Healthcare staff review AI-generated drafts before sending, maintaining clinical oversight while dramatically reducing response preparation time.

Organizations deploying patient communication automation report:

  • Higher patient activation scores versus traditional patient portals
  • Response time reductions from hours or days to minutes
  • Staff capacity freed for complex clinical inquiries requiring expertise
  • Improved patient satisfaction through consistent, timely communication

The multi-user authorization challenge becomes evident here: each AI response must access only the specific patient data authorized for that inquiry, maintain proper consent boundaries, and operate within the scope granted to the healthcare provider handling the communication. Without proper MCP runtime governance, organizations risk HIPAA violations through excessive data access.

Clinical Documentation and Ambient Scribing

Documentation burden contributes significantly to clinician burnout, with physicians spending 35% of time documenting patient data. This administrative overhead reduces face-to-face patient time and contributes to medical errors when documentation is rushed or incomplete.

Ambient AI captures clinical conversations during patient visits while MCP connections retrieve patient context—medical history, current medications, recent lab results—from the EHR in real-time. The AI synthesizes the discussion with retrieved contextual data to generate structured clinical notes matching specialty-specific templates. Physicians review and attest to AI-generated documentation, maintaining clinical responsibility while reclaiming hours previously spent on manual note-taking.

Healthcare organizations implementing ambient documentation through MCP report:

  • Significant time returned to direct patient care daily per physician
  • Improved documentation quality and completeness
  • Reduced physician burnout indicators in workforce surveys
  • Higher patient engagement scores when physicians maintain eye contact versus computer focus

The authorization complexity here demands careful governance: AI must read comprehensive patient histories but write only to specific documentation fields, operating within scope limitations that prevent unintended data modifications across the EHR system.

Healthcare Data Analytics Through Natural Language Queries

Healthcare data warehouses contain vast clinical and operational information, but only SQL-proficient analysts can traditionally query this data. Business users—care coordinators, quality managers, and executives—must submit data requests and wait days for reports, slowing decision-making and limiting data accessibility for frontline staff.

MCP servers like Snowflake's implementation enable AI to convert plain-language questions into SQL queries. Care coordinators can ask "Show me readmission rates for diabetic patients in Q1" and receive instant visualizations without technical expertise. Quality managers identify care gaps through conversational queries rather than waiting for analyst availability.

Organizations deploying natural language analytics report:

  • Improved productivity for care coordinators equipped with self-service analytics
  • Elimination of data request backlogs freeing analyst capacity for complex projects
  • Faster identification of care gaps and quality improvement opportunities
  • Better-informed decision-making at all organizational levels

Implementation requires semantic model configuration defining business metrics and their relationships—essentially creating a business-friendly translation layer over technical database schemas. Organizations typically achieve value within 2-3 weeks of deployment.

Clinical Decision Support at Point of Care

Clinicians must synthesize information from multiple sources during patient encounters: patient data from EHRs, clinical guidelines, drug interaction databases, and current medical literature. Manual lookup is time-consuming and prone to oversight, particularly when treating complex patients with multiple comorbidities.

AI-powered clinical decision support uses MCP to simultaneously query EHR patient data through FHIR connections, clinical guideline databases indexed in Elasticsearch, drug interaction databases, and medical literature repositories. The system provides contextualized recommendations embedded directly in EHR workflow, supporting evidence-based care without disrupting clinical processes.

Healthcare organizations implementing comprehensive clinical decision support report:

  • 30-50% reduction in medication errors through CDSS capabilities
  • Improved evidence-based care protocol adherence
  • Faster clinical decision-making during complex patient encounters
  • Reduced diagnostic errors through comprehensive information synthesis

This use case exemplifies why proper MCP runtime architecture matters: the AI must access comprehensive patient data, query multiple external knowledge sources, and present recommendations—all while maintaining audit trails showing exactly which data informed each suggestion for regulatory compliance and clinical liability protection.

Best Practices for Enterprise MCP Implementation

Architecting Multi-User Authorization for Healthcare

The fundamental challenge in healthcare AI isn't simply logging users into systems through OAuth. The critical requirement is multi-user authorization: ensuring each AI agent operates with precisely the right permissions and scopes when acting on behalf of specific users across multiple systems.

Traditional API integrations create brittle point-to-point connections that don't scale when you need agents accessing dozens of systems on behalf of hundreds of users with varying role-based permissions. Building this multi-user authorization infrastructure internally requires substantial engineering resources:

  • OAuth 2.1 implementation for each integrated system
  • Token management with proper refresh lifecycle handling
  • Permission mapping between organizational roles and system-specific scopes
  • Session management maintaining authorization state across multi-step workflows
  • Audit logging capturing every authorization grant and data access

Without specialized infrastructure, healthcare IT teams face months of development work for each new AI use case. Platforms like Arcade as MCP runtime handle this complexity, providing pre-built authorization flows, token lifecycle management, and comprehensive audit trails out of the box. This infrastructure enables AI/ML teams to focus on building valuable clinical applications rather than reimplementing authorization plumbing.

For security teams, proper MCP architecture provides the governance layer needed to meet HIPAA requirements: every agent action is attributable to a specific user, operates within defined permission boundaries, and generates audit evidence for compliance reviews. Business leaders gain confidence deploying AI knowing the authorization infrastructure meets regulatory standards.

Implementing HIPAA-Compliant Security Controls

Healthcare MCP implementations must meet stringent HIPAA technical safeguards. The Healthcare MCP extension provides built-in compliance features that generic MCP servers lack:

Patient Identity Segregation: HMCP provides tenant-aware data isolation ensuring AI agents can only access patients within authorized organizational boundaries. This prevents accidental cross-organization data exposure in multi-tenant environments.

Minimum Necessary Access: Rather than granting broad system access, MCP configurations enforce field-level permissions. An AI generating appointment reminders accesses only scheduling data and contact information, not full clinical histories. An AI supporting clinical documentation accesses comprehensive patient records but writes only to specific note fields.

Encryption and Token Management: Tokens encrypted at rest and industry-standard OAuth 2.0 with proper token management and permission scoping protect credentials from exposure. Importantly, platforms handling token and secret management don't store actual patient data—they manage the multi-user authorization layer enabling secure data access.

Audit Trail Completeness: Every agent action generates audit records capturing user identity, timestamp, query content, and data returned. These trails support HIPAA's accounting of disclosures requirements and provide evidence for security incident investigations.

Rate Limiting and Anomaly Detection: Protection against excessive queries or potential attacks prevents both system performance degradation and unauthorized data harvesting attempts.

Independent security certifications and third-party audits demonstrate validated compliance with these controls. For healthcare providers evaluating MCP platforms, look for vendors that can show:

  • Just-in-time authorization mechanisms validated by independent auditors
  • Tool-level access controls that inherit from existing identity providers
  • Complete audit trails for every agent action
  • Deployment options that support highly restricted, air-gapped environments when required

Establishing Governance Before Deployment

MCP gives AI agents autonomous access to healthcare systems. Without strong governance frameworks established upfront, organizations risk HIPAA violations, clinical errors, and loss of stakeholder trust. Best practice requires governance committees formed before initial deployment including:

  • Clinical leadership validating medical accuracy standards
  • Compliance officers ensuring regulatory requirement adherence
  • IT security establishing technical safeguard baselines
  • Privacy officers defining minimum necessary access policies
  • Quality management setting monitoring and audit protocols

Human-in-the-Loop for High-Stakes Actions: AI should assist clinical judgment, not replace it. Implement approval workflows for high-stakes actions including medication orders, clinical recommendations affecting treatment plans, and diagnosis-related documentation. AI-generated draft content undergoes clinician review before execution, maintaining professional accountability.

Start with Single Use Cases: Rather than attempting enterprise-wide AI transformation immediately, implement one well-defined use case to production first. Patient communication automation or data analytics present lower clinical risk than diagnostic AI or medication management. Demonstrate measurable ROI, refine governance processes, and build organizational confidence before scaling to additional use cases.

Continuous Monitoring Requirements: Production MCP deployments require ongoing oversight, not just initial validation:

  • Quarterly audit of MCP access logs reviewing data access patterns
  • Regular revalidation of AI accuracy metrics against clinical gold standards
  • Monthly updates to clinical knowledge bases (guidelines, drug databases, formularies)
  • Monitoring for model drift with retraining or adjustment as needed
  • Change management processes for MCP server version updates

Healthcare has entered what analysts call the "prove-it era" of AI: systems must demonstrate measurable results—improved efficiency, better outcomes, reduced waste—not just experimental potential. Governance frameworks ensure MCP implementations deliver validated value rather than becoming expensive theoretical infrastructure.

Leveraging Schema Markup and Interoperability Standards

Healthcare MCP implementations benefit significantly from proper schema implementation and standards adoption. FHIR MCP servers provide native access to standardized clinical data resources, enabling AI agents to query patient demographics, clinical observations, medications, procedures, and diagnostic reports through consistent interfaces regardless of underlying EHR vendor.

LOINC Validation Prevents Hallucination: One critical advantage of healthcare-specific MCP implementations is built-in medical terminology validation. Generic AI models sometimes hallucinate medical codes—generating plausible-looking but invalid LOINC codes for lab tests or ICD codes for diagnoses. FHIR MCP servers with integrated LOINC validation prevent these errors by verifying all generated codes against authoritative terminologies before system execution.

Bidirectional Data Flow with Audit Controls: Modern MCP implementations support both reading from and writing to healthcare systems when properly authorized. This enables AI agents to not only retrieve patient data but also create appointment records, generate clinical notes, submit orders, and update care plans—all with appropriate approval workflows and comprehensive audit trails documenting each modification.

Integration with Existing Identity Providers: Rather than creating separate user management systems, production MCP architectures inherit permissions from existing organizational identity providers. A physician's Active Directory group memberships or Okta role assignments automatically determine which MCP tools and data sources the AI can access when acting on their behalf. This inheritance model ensures consistent permission management and simplifies compliance by maintaining single sources of truth for access control.

Addressing Technical Debt and Legacy System Integration

Many healthcare organizations operate legacy systems lacking modern FHIR APIs or even basic RESTful interfaces. MCP provides migration pathways avoiding complete system replacement:

Database MCP Toolboxes: For systems with accessible databases but limited APIs, database MCP connectors enable direct SQL query access through AI-friendly natural language interfaces. While less ideal than API-based access, this approach unlocks legacy data without requiring application modernization.

HL7 v2 Adapters: Organizations with extensive HL7 v2 message infrastructure can implement translation layers converting traditional HL7 messages into FHIR resources accessible through MCP. This preserves existing integration investments while adding AI capabilities.

Incremental Adoption: MCP runs alongside existing integrations during transition periods. Organizations can maintain current point-to-point API connections while gradually migrating use cases to MCP architecture, reducing migration risk and enabling phased rollouts.

The key insight: MCP doesn't require complete infrastructure replacement. Strategic deployment addresses specific high-value use cases while legacy systems continue operating, providing ROI during gradual modernization rather than requiring massive upfront transformation investments.

Agentic Commerce in Healthcare Procurement

The emergence of agentic commerce platforms introduces new authorization challenges and opportunities for healthcare supply chain management. AI agents can now autonomously search medical supply inventories, compare pricing across vendors, and complete purchase transactions—all while maintaining proper spending controls and approval workflows.

For healthcare organizations, this capability addresses procurement inefficiencies where staff manually research supplies, compare vendor catalogs, negotiate pricing, and process orders across fragmented systems. MCP-enabled agentic commerce connects AI to supply chain platforms, purchasing systems, and vendor APIs through standardized interfaces.

Transaction-Specific Authorization: Unlike traditional procurement requiring standing purchase order authority, agentic commerce enables granular transaction controls:

  • Single-use virtual cards locked to specific merchants and exact amounts
  • Automatic spend limit enforcement preventing unauthorized purchases
  • User approval required for each transaction rather than blanket purchasing authority
  • Complete transaction observability with audit trails for every purchase decision

No Persistent Payment Storage: Security-focused implementations generate just-in-time payment credentials for specific transactions then invalidate them immediately after completion, eliminating the risk of stored credential compromise that traditional procurement systems face.

This authorization model particularly benefits healthcare organizations where purchasing decisions require clinical validation (ensuring supplies meet patient care requirements) combined with financial controls (staying within departmental budgets). AI agents can propose optimal purchasing decisions based on clinical need, inventory levels, and pricing, while human approvers validate transactions before execution.

Multi-Agent Systems and Collaborative Authorization

Healthcare workflows increasingly require multiple specialized AI agents collaborating on complex tasks. A patient discharge planning workflow might involve:

  • A clinical documentation agent summarizing hospital stay and treatment plans
  • A medication reconciliation agent verifying post-discharge prescriptions
  • A care coordination agent scheduling follow-up appointments
  • An insurance verification agent confirming coverage for prescribed services
  • A patient communication agent sending discharge instructions and medication reminders

Traditional authorization models granting each agent full system access create security risks and violate minimum necessary principles. Modern MCP implementations support agent-to-agent authorization patterns where agents hand off specific, scoped permissions for discrete workflow steps.

Multi-agent architectures enable workflow specialization: each agent maintains narrow expertise and authorization scope rather than building monolithic agents with excessive permissions. This aligns with both security best practices (least privilege) and software engineering principles (separation of concerns).

For healthcare executives, multi-agent systems promise more maintainable AI infrastructure: when clinical guidelines change, you update the specialized clinical decision support agent rather than retraining multiple general-purpose agents. When regulatory requirements evolve, you modify the compliance-checking agent without touching clinical workflow agents.

Implementation requires sophisticated MCP runtimes managing authorization handoffs between agents, maintaining audit trails across multi-step workflows, and ensuring each agent operates only within its designated scope. Platforms like Arcade's LangGraph integration provide this orchestration layer: LangGraph is LangChain’s graph-based framework for managing complex, multi-step agent workflows, while Arcade’s MCP runtime supplies the multi-user authorization, token and secret management, and tool catalog governance that keep those workflows safe in production.

Production-Ready Authorization with Independent Validation

The maturation of healthcare AI from experimental projects to production deployments demands independently validated security controls. 70% of AI projects fail security review before reaching production, typically because authorization implementations don't meet enterprise compliance standards.

For MCP platforms serving healthcare organizations, independent security assessments and long-running audits matter more than marketing claims. Executives should look for:

Validated Authorization Mechanisms: Independent auditors confirming that just-in-time authorization processes properly scope permissions, enforce minimum necessary access, and maintain separation between users and organizational tenants.

Audit Trail Completeness: Evidence that every agent action generates comprehensive audit records meeting healthcare compliance requirements including user attribution, timestamp accuracy, and data access logging.

Security Control Effectiveness: Ongoing validation that access controls, encryption, and multi-user authorization workflows remain effective as systems scale and evolve.

Vendor Risk Reduction: Standardized, audited controls that shorten security reviews and reduce the amount of bespoke due diligence required for each AI implementation.

This shift reflects healthcare AI's evolution from point solutions requiring custom security validation to infrastructure platforms with standardized, independently validated controls that accelerate deployment while maintaining compliance.

The Convergence of MCP and Healthcare Interoperability Standards

Healthcare interoperability has long struggled with fragmented, domain-specific standards. HL7 v2 messages for lab orders differ from pharmacy system interfaces, which differ from imaging system protocols, which differ from billing system APIs. This fragmentation created the integration nightmare MCP addresses.

The convergence of MCP with established healthcare standards—particularly FHIR—creates a powerful combination:

  • FHIR provides semantic standardization: Common data models for clinical concepts
  • MCP provides integration standardization: Common protocols for AI access to those data models

Organizations implementing FHIR MCP servers gain both: AI agents query standardized clinical data resources through standardized integration protocols, dramatically reducing integration complexity while improving data consistency.

How Arcade Accelerates Healthcare AI Authorization

While understanding MCP fundamentals is essential, partnering with a specialized MCP runtime purpose-built for production multi-user authorization amplifies results exponentially. Arcade's MCP runtime provides the multi-user authorization infrastructure healthcare organizations need to deploy AI agents that securely act on behalf of users across clinical and operational systems.

Arcade addresses the core multi-user authorization challenge: enabling AI agents to operate with precisely the right permissions and scopes when accessing EHRs, data warehouses, communication systems, and operational platforms on behalf of physicians, nurses, administrators, and other healthcare staff. This isn't just OAuth login—it's comprehensive token and secret management, granular permission scoping, and complete audit trail generation for every agent action.

For AI/ML teams, Arcade eliminates months of multi-user authorization infrastructure development. Pre-built integrations for Gmail, Slack, Google Calendar, and hundreds of other platforms connect to your AI agents through Arcade's tool catalog, with multi-user authorization flows, token refresh, and permission management handled automatically. When you need systems that aren’t yet in the catalog, Arcade’s MCP framework lets your teams build new tools that plug into the same runtime and governance model—without changing how agents are designed. Arcade.dev manages tokens and secrets, not patient data, so credentials stay protected while underlying systems remain the systems of record.

Security teams gain the governance layer HIPAA compliance demands. With SOC 2 Type 2 certification, Arcade.dev becomes the authorized path to production with these key points:

  • Just-in-time authorization validated by independent auditors
  • Tool-level access controls that inherit from existing identity providers
  • Complete audit trails for every agent action
  • VPC deployment options for air-gapped environments

Business leaders accelerate time-to-value by implementing single use cases to production quickly, demonstrating ROI, then scaling to additional applications. Arcade's infrastructure supports this phased approach: start with patient communication automation using the Gmail agent toolkit, prove value within weeks, then expand to clinical documentation, data analytics, or other use cases leveraging the same authorization foundation.

LangGraph integration enables sophisticated multi-agent workflows: LangGraph, as LangChain’s graph-based agent framework, coordinates complex, multi-step flows, while Arcade’s MCP runtime enforces multi-user authorization boundaries. Each specialized agent in your discharge planning workflow or clinical decision support system operates with scoped permissions appropriate to its function, with Arcade managing token and secret usage, authorization handoffs, and comprehensive audit trails across complex multi-step processes.

Frequently Asked Questions

How does MCP address HIPAA compliance requirements that traditional API integrations often violate?

MCP implementations designed for healthcare—particularly Healthcare MCP (HMCP) extensions—provide built-in HIPAA technical safeguards that generic integrations lack. These include patient identity segregation ensuring tenant-aware data isolation, minimum necessary access controls enforcing field-level permissions rather than broad system access, and comprehensive audit trails logging every data access with user attribution and timestamps. Generic MCP servers require extensive security hardening to meet healthcare standards, while HMCP implementations include compliance features by design.

What is the difference between authentication and the multi-user authorization challenge MCP addresses?

Authentication simply verifies user identity through OAuth login or similar mechanisms. The far more complex challenge is multi-user authorization: ensuring each AI agent operates with precisely the right permissions and scopes when acting on behalf of specific users across multiple systems. A physician accessing patient records requires different permissions than a billing clerk accessing the same EHR. MCP runtimes like Arcade manage these granular permission mappings, token lifecycle across multi-step workflows, and audit trails documenting authorization decisions—infrastructure that would require months of custom development without specialized platforms.

Can smaller healthcare organizations with limited IT resources implement MCP, or is this only feasible for large health systems?

Smaller organizations often achieve faster MCP deployment than large health systems due to simpler approval processes and fewer legacy integration constraints. Managed MCP platforms handle infrastructure complexity, enabling small IT teams to focus on use case definition and clinical validation rather than building authorization infrastructure from scratch. Starting with non-clinical use cases like patient communication automation through pre-built integrations (Gmail, scheduling systems) provides low-risk entry points requiring minimal technical expertise.

How do organizations measure ROI from MCP implementations to justify continued investment beyond pilot projects?

Measurable outcomes vary by use case but should include quantitative metrics validated through data analysis: time savings per transaction or workflow (prior authorization processing hours, documentation minutes per encounter), error reduction percentages (medication errors, claim denials, diagnostic oversights), cost savings through reduced administrative overhead, and patient experience improvements through satisfaction surveys. Organizations should establish baseline measurements before deployment, track metrics throughout pilot periods, and calculate break-even points considering both implementation costs and ongoing operational savings. Healthcare has entered the "prove-it era" of AI where executive support requires demonstrated value, not theoretical benefits.

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